Endocrine Abstracts

Vitamin D deficiency seems to be more prevalent in patients with primary hyperparathyroidism (PHPT) than in general population. This association has many clinical and therapeutic implications.The aim of this study was to assess the vitamin D status of patients with PHPT and to describe the clinical presentation of the disease when vitamin D deficiency is associated.Methods: We studied in a retrospective manner, the case of seven pa...

Insulinoma is a very rare type of islet cell tumor. The aim of our study is to report our clinical experience with insulinoma in order to determine clinical, biological, radiological and therapeutic particularities of this tumor type.It’s a retrospective study, including five patients (three women and two men) referred to our department between 2005 and 2011 for hypoglycemia exploration. Mean age of our group is 39.8±15.4 years (ranges: 20&#150...

Introduction: Cushing’s disease (CD) is a condition due to an ACTH-secreting pituitary adenoma and leading to hypercorticism. Hirsutism is common in CD but its exact frequency has been poorly studied. It results from the stimulating effect of ACTH on adrenal production of androgens.The aim of this study is to determine the androgenic profile in hirsute patients with CD.Patients and methods: It is a retrospective study of nine ...

Sleep apnoea syndrome (SAS) is common in acromegaly and both diseases are independently associated with hypertension and insulin resistance contributing to increased morbidity and mortality.The aim of this study was to assess the prevalence and risk factors of SAS in acromegaly, to study clinical and polysomnographic particularities of SAS in acromegaly and to analyze the effects of acromegaly treatment on SAS.It’s a retrospec...

Introduction: Cushing disease (CD) is a condition due to an ACTH-secreting pituitary adenoma that is usually a microadenoma. Seldom, the lesion may be atypical by his size or his radiological aspect.The aim of this study is to analyze the clinical and biological data of CD with atypical radiological aspect (macroadenoma or other), to compare them to those of CD with a typical radiological aspect (microadenoma) and to determine the clinical or biological ...

Most macroprolactinomas are responsive to dopamine against drugs. Bromocriptine (BRC) has been available and extensively used in our country. The aims are to assess the outcome in 29 patients with macroprolactinomas who were treated with BRC.Material and methods: A multicentric study of 29 patients with macroprolactinoma (19 female; 10 males). The mean age was 33 years. The pituitary mass was larger than 10 mm in diameter. There was no endocrinological e...